P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

Type 1 diabetes (T1D) causes a range of skeletal problems, including reduced bone density and increased risk for bone fractures. However, mechanisms underlying skeletal complications in diabetes are still not well understood. We hypothesize that high glucose levels in T1D alters expression and funct...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Seref-Ferlengez, Zeynep, Maung, Stephanie, Schaffler, Mitchell B., Spray, David C., Suadicani, Sylvia O., Thi, Mia M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861344/
https://ncbi.nlm.nih.gov/pubmed/27159053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155107
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