Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study

BACKGROUND: Defining optimal routes for induction of mucosal immunity represents an important research priority for the HIV-1 vaccine field. In particular, it remains unclear whether mucosal routes of immunization can improve mucosal immune responses. METHODS: In this randomized two center phase I c...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Cosgrove, Catherine A., Lacey, Charles J., Cope, Alethea V., Bartolf, Angela, Morris, Georgina, Yan, Celine, Baden, Susan, Cole, Tom, Carter, Darrick, Brodnicki, Elizabeth, Shen, Xiaoying, Joseph, Sarah, DeRosa, Stephen C., Peng, Lili, Yu, Xuesong, Ferrari, Guido, Seaman, Mike, Montefiori, David C., Frahm, Nicole, Tomaras, Georgia D., Stöhr, Wolfgang, McCormack, Sheena, Shattock, Robin J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861263/
https://ncbi.nlm.nih.gov/pubmed/27159166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152038
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