ATM Regulates a RASSF1A-Dependent DNA Damage Response

Hypermethylation of CpG islands in the RASSF1 promoter is one of the most frequent events identified in human cancer [1–3]. The epigenetic-driven loss of RASSF1A protein expression is observed more often in tumors of higher grade and correlates with a decreased responsiveness to DNA-damaging therapy...

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Detaylı Bibliyografya
Yayımlandı:Curr Biol
Asıl Yazarlar: Hamilton, Garth, Yee, Karen S., Scrace, Simon, O’Neill, Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861209/
https://ncbi.nlm.nih.gov/pubmed/19962312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.10.040
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