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ATM Regulates a RASSF1A-Dependent DNA Damage Response
Hypermethylation of CpG islands in the RASSF1 promoter is one of the most frequent events identified in human cancer [1–3]. The epigenetic-driven loss of RASSF1A protein expression is observed more often in tumors of higher grade and correlates with a decreased responsiveness to DNA-damaging therapy...
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| Publicado no: | Curr Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861209/ https://ncbi.nlm.nih.gov/pubmed/19962312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.10.040 |
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