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A Novel ATM-Dependent Pathway Regulates Protein Phosphatase 1 in Response to DNA Damage
Protein phosphatase 1 (PP1), a major protein phosphatase important for a variety of cellular responses, is activated in response to ionizing irradiation (IR)-induced DNA damage. Here, we report that IR induces the rapid dissociation of PP1 from its regulatory subunit inhibitor-2 (I-2) and that the p...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2293124/ https://ncbi.nlm.nih.gov/pubmed/18250156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01711-07 |
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