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ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses
Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase with a master regulatory function in the DNA damage response. In this role, ATM commands a complex biochemical network that signals the presence of oxidative DNA damage, including the dangerous DNA double-strand break, and faci...
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Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Royal Society
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577461/ https://ncbi.nlm.nih.gov/pubmed/28847820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0283 |
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