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ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses

Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase with a master regulatory function in the DNA damage response. In this role, ATM commands a complex biochemical network that signals the presence of oxidative DNA damage, including the dangerous DNA double-strand break, and faci...

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Détails bibliographiques
Publié dans:Philos Trans R Soc Lond B Biol Sci
Auteurs principaux: Berger, N. Daniel, Stanley, Fintan K. T., Moore, Shaun, Goodarzi, Aaron A.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577461/
https://ncbi.nlm.nih.gov/pubmed/28847820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0283
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