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p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

Alzheimer’s disease (AD) is the most common type of dementia and age-related neurodegenerative disease. Elucidating the cellular changes that occur during ageing is an important step towards understanding the pathogenesis and progression of neurodegenerative disorders. SIRT6 is a member of the mamma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jung, Eun Sun, Choi, Hyunjung, Song, Hyundong, Hwang, Yu Jin, Kim, Ahbin, Ryu, Hoon, Mook-Jung, Inhee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860716/
https://ncbi.nlm.nih.gov/pubmed/27156849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25628
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