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The impact of amplification on differential expression analyses by RNA-seq

Currently, quantitative RNA-seq methods are pushed to work with increasingly small starting amounts of RNA that require amplification. However, it is unclear how much noise or bias amplification introduces and how this affects precision and accuracy of RNA quantification. To assess the effects of am...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Parekh, Swati, Ziegenhain, Christoph, Vieth, Beate, Enard, Wolfgang, Hellmann, Ines
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860583/
https://ncbi.nlm.nih.gov/pubmed/27156886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25533
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