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A systematic evaluation of single cell RNA-seq analysis pipelines

The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and computational pipelines for which best practices have not yet been established. Here, we use simulations based on five scRNA-seq library protocols in combination with nine realis...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Vieth, Beate, Parekh, Swati, Ziegenhain, Christoph, Enard, Wolfgang, Hellmann, Ines
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789098/
https://ncbi.nlm.nih.gov/pubmed/31604912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12266-7
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