Pharmacokinetic interaction study between riociguat and the combined oral contraceptives levonorgestrel and ethinylestradiol in healthy postmenopausal women

Abstract. Female patients requiring treatment for pulmonary arterial hypertension (PAH) are advised to avoid pregnancy because of the high associated mortality rate. Oral contraception is one of the main methods of preventing pregnancy in this context, mandating pharmacokinetic and safety studies fo...

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Bibliographic Details
Published in:Pulm Circ
Main Authors: Frey, Reiner, Unger, Sigrun, van der Mey, Dorina, Becker, Corina, Saleh, Soundos, Wensing, Georg, Mück, Wolfgang
Format: Artigo
Language:Inglês
Published: University of Chicago Press 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860538/
https://ncbi.nlm.nih.gov/pubmed/27162633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685428
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