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Pharmacokinetic interaction study between riociguat and the combined oral contraceptives levonorgestrel and ethinylestradiol in healthy postmenopausal women

Abstract. Female patients requiring treatment for pulmonary arterial hypertension (PAH) are advised to avoid pregnancy because of the high associated mortality rate. Oral contraception is one of the main methods of preventing pregnancy in this context, mandating pharmacokinetic and safety studies fo...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Frey, Reiner, Unger, Sigrun, van der Mey, Dorina, Becker, Corina, Saleh, Soundos, Wensing, Georg, Mück, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860538/
https://ncbi.nlm.nih.gov/pubmed/27162633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685428
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