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Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat
Oral riociguat is a soluble guanylate cyclase (sGC) stimulator that targets the nitric oxide (NO)–sGC–cyclic guanosine monophosphate pathway with a dual mode of action: directly by stimulating sGC, and indirectly by increasing the sensitivity of sGC to NO. It is rapidly absorbed, displays almost com...
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| Publicado no: | Clin Pharmacokinet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974002/ https://ncbi.nlm.nih.gov/pubmed/29086344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0604-7 |
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