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Population pharmacokinetics of single-dose riociguat in patients with renal or hepatic impairment
Abstract. This population pharmacokinetics (PK) analysis characterized the PK of the oral soluble guanylate cyclase stimulator riociguat in patients with renal or hepatic impairment and determined whether smoking affects riociguat dosing. Two phase 1 studies were performed in patients with renal imp...
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| Pubblicato in: | Pulm Circ |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
University of Chicago Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860534/ https://ncbi.nlm.nih.gov/pubmed/27162631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685647 |
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