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METTL3 promotes translation in human cancer cells
METTL3 is a RNA methyltransferase implicated in mRNA biogenesis, decay, and translation control through N(6)-methyladenosine (m(6)A) modification. Here we find that METTL3 promotes translation of certain mRNAs including epidermal growth factor receptor (EGFR) and the Hippo pathway effector TAZ in hu...
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| Publicat a: | Mol Cell |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860043/ https://ncbi.nlm.nih.gov/pubmed/27117702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.021 |
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