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METTL3 promotes translation in human cancer cells

METTL3 is a RNA methyltransferase implicated in mRNA biogenesis, decay, and translation control through N(6)-methyladenosine (m(6)A) modification. Here we find that METTL3 promotes translation of certain mRNAs including epidermal growth factor receptor (EGFR) and the Hippo pathway effector TAZ in hu...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Lin, Shuibin, Choe, Junho, Du, Peng, Triboulet, Robinson, Gregory, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860043/
https://ncbi.nlm.nih.gov/pubmed/27117702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.021
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