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The multifaceted role of CD4(+) T cells in the regulation of CD8(+) T cell memory maturation

Following infection, T cells differentiate into a heterogeneous population of effector T cells that can mediate pathogen clearance. A subset of these effector T cells possesses the ability to survive long-term and mature into memory T cells capable of providing long-term immunity. Understanding the...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Immunol
Hauptverfasser: Laidlaw, Brian J., Craft, Joe, Kaech, Susan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860014/
https://ncbi.nlm.nih.gov/pubmed/26781939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2015.10
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