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An Interleukin-21- Interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8(+) T cells

Memory CD8(+) T cells are the pivotal component of adaptive immunity, however the signal and genetic pathways that govern their formation remain poorly defined. This study shows that the IL-10-IL-21-STAT3 pathway is critical for memory CD8(+) T cell development following acute LCMV infection. In the...

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Detalhes bibliográficos
Main Authors: Cui, Weiguo, Liu, Ying, Weinstein, Jason S., Craft, Joseph, Kaech, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431922/
https://ncbi.nlm.nih.gov/pubmed/22118527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.09.017
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