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Coordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21

TRIM21 is a high-affinity antibody receptor uniquely expressed in the cytosol of mammalian cells. Here we summarize its role in extending antibody protection into the intracellular environment and allowing nonprofessional cells to benefit from adaptive immunity. We highlight recent work that has she...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fletcher, Adam J., James, Leo C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859718/
https://ncbi.nlm.nih.gov/pubmed/26937031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00050-16
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