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Enhancement of Transcription by a Splicing-Competent Intron Is Dependent on Promoter Directionality

Enhancement of transcription by a splicing-competent intron is an evolutionarily conserved feature among eukaryotes. The molecular mechanism underlying the phenomenon, however, is not entirely clear. Here we show that the intron is an important regulator of promoter directionality. Employing strand-...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Agarwal, Neha, Ansari, Athar
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859611/
https://ncbi.nlm.nih.gov/pubmed/27152651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006047
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