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Enhancement of Transcription by a Splicing-Competent Intron Is Dependent on Promoter Directionality

Enhancement of transcription by a splicing-competent intron is an evolutionarily conserved feature among eukaryotes. The molecular mechanism underlying the phenomenon, however, is not entirely clear. Here we show that the intron is an important regulator of promoter directionality. Employing strand-...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Agarwal, Neha, Ansari, Athar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859611/
https://ncbi.nlm.nih.gov/pubmed/27152651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006047
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