EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line

The Epidermal Growth Factor Receptor (EGFR) and its mutations contribute in various ways to tumorigenesis and biology of human cancers. They are associated with tumor proliferation, progression, drug resistance and the process of apoptosis. There are also reports that overexpression and activation o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Treda, Cezary, Popeda, Marta, Ksiazkiewicz, Magdalena, Grzela, Dawid P., Walczak, Maciej P., Banaszczyk, Mateusz, Peciak, Joanna, Stoczynska-Fidelus, Ewelina, Rieske, Piotr
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859505/
https://ncbi.nlm.nih.gov/pubmed/27153109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155230
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