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Cell line with endogenous EGFR(vIII) expression is a suitable model for research and drug development purposes
Glioblastoma is the most common and malignant brain tumor, characterized by high cellular heterogeneity. About 50% of glioblastomas are positive for EGFR amplification, half of which express accompanying EGFR mutation, encoding truncated and constitutively active receptor termed EGFR(vIII). Currentl...
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出版年: | Oncotarget |
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主要な著者: | , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Impact Journals LLC
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077985/ https://ncbi.nlm.nih.gov/pubmed/27004406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8201 |
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