The Failure in the Stabilization of Glioblastoma-Derived Cell Lines: Spontaneous In Vitro Senescence as the Main Culprit

Cell line analysis is an important element of cancer research. Despite the progress in glioblastoma cell culturing, the cells isolated from the majority of specimens cannot be propagated infinitely in vitro. The aim of this study was to identify the processes responsible for the stabilization failur...

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Detalhes bibliográficos
Main Authors: Stoczynska-Fidelus, Ewelina, Piaskowski, Sylwester, Bienkowski, Michal, Banaszczyk, Mateusz, Hulas-Bigoszewska, Krystyna, Winiecka-Klimek, Marta, Radomiak-Zaluska, Anna, Och, Waldemar, Borowiec, Maciej, Zieba, Jolanta, Treda, Cezary, Rieske, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910690/
https://ncbi.nlm.nih.gov/pubmed/24498027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087136
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