Testosterone Antagonizes Doxorubicin‐Induced Senescence of Cardiomyocytes

BACKGROUND: Chronic cardiotoxicity is less common in male than in female patients receiving doxorubicin and other anthracyclines at puberty and adolescence. We hypothesized that this sex difference might be secondary to distinct activities of sex hormones on cardiomyocyte senescence, which is though...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Altieri, Paola, Barisione, Chiara, Lazzarini, Edoardo, Garuti, Anna, Bezante, Gian Paolo, Canepa, Marco, Spallarossa, Paolo, Tocchetti, Carlo Gabriele, Bollini, Sveva, Brunelli, Claudio, Ameri, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859360/
https://ncbi.nlm.nih.gov/pubmed/26746999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002383
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