Inhibition of Doxorubicin-Induced Senescence by PPARδ Activation Agonists in Cardiac Muscle Cells: Cooperation between PPARδ and Bcl6

Senescence and apoptosis are two distinct cellular programs that are activated in response to a variety of stresses. Low or high doses of the same stressor, i.e., the anticancer drug doxorubicin, may either induce apoptosis or senescence, respectively, in cardiac muscle cells. We have demonstrated t...

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Detalhes bibliográficos
Main Authors: Altieri, Paola, Spallarossa, Paolo, Barisione, Chiara, Garibaldi, Silvano, Garuti, Anna, Fabbi, Patrizia, Ghigliotti, Giorgio, Brunelli, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458009/
https://ncbi.nlm.nih.gov/pubmed/23049957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046126
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