Testosterone Antagonizes Doxorubicin‐Induced Senescence of Cardiomyocytes

BACKGROUND: Chronic cardiotoxicity is less common in male than in female patients receiving doxorubicin and other anthracyclines at puberty and adolescence. We hypothesized that this sex difference might be secondary to distinct activities of sex hormones on cardiomyocyte senescence, which is though...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Altieri, Paola, Barisione, Chiara, Lazzarini, Edoardo, Garuti, Anna, Bezante, Gian Paolo, Canepa, Marco, Spallarossa, Paolo, Tocchetti, Carlo Gabriele, Bollini, Sveva, Brunelli, Claudio, Ameri, Pietro
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859360/
https://ncbi.nlm.nih.gov/pubmed/26746999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002383
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