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CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia
BACKGROUND: Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm of childhood whose clinical heterogeneity is only poorly represented by gene sequence alterations. It was previously shown that aberrant DNA methylation of distinct target genes defines a more aggressive variant of...
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| Publicat a: | Clin Epigenetics |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858931/ https://ncbi.nlm.nih.gov/pubmed/27158276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0216-3 |
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