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RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia
Aberrant DNA methylation at specific genetic loci is a key molecular feature of juvenile myelomonocytic leukemia (JMML) with poor prognosis. Using quantitative high-resolution mass spectrometry, we identified RASA4 isoform 2, which maps to chromosome 7 and encodes a member of the GAP1 family of GTPa...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169017/ https://ncbi.nlm.nih.gov/pubmed/25147919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29941 |
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