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Triallelic Population Genomics for Inferring Correlated Fitness Effects of Same Site Nonsynonymous Mutations
The distribution of mutational effects on fitness is central to evolutionary genetics. Typical univariate distributions, however, cannot model the effects of multiple mutations at the same site, so we introduce a model in which mutations at the same site have correlated fitness effects. To infer the...
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| 發表在: | Genetics |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Genetics Society of America
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858796/ https://ncbi.nlm.nih.gov/pubmed/27029732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.184812 |
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