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Triallelic Population Genomics for Inferring Correlated Fitness Effects of Same Site Nonsynonymous Mutations
The distribution of mutational effects on fitness is central to evolutionary genetics. Typical univariate distributions, however, cannot model the effects of multiple mutations at the same site, so we introduce a model in which mutations at the same site have correlated fitness effects. To infer the...
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| Опубликовано в: : | Genetics |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858796/ https://ncbi.nlm.nih.gov/pubmed/27029732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.184812 |
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