Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans

IMPORTANCE: Evolutionary medicine may provide insights into human physiology and pathophysiology, including tumor biology. OBJECTIVE: To identify mechanisms for cancer resistance in elephants and compare cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patien...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Abegglen, Lisa M., Caulin, Aleah F., Chan, Ashley, Lee, Kristy, Robinson, Rosann, Campbell, Michael S., Kiso, Wendy K., Schmitt, Dennis L., Waddell, Peter J, Bhaskara, Srividya, Jensen, Shane T., Maley, Carlo C., Schiffman, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858328/
https://ncbi.nlm.nih.gov/pubmed/26447779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2015.13134
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