Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans

IMPORTANCE: Evolutionary medicine may provide insights into human physiology and pathophysiology, including tumor biology. OBJECTIVE: To identify mechanisms for cancer resistance in elephants and compare cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patien...

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Bibliografische gegevens
Gepubliceerd in:JAMA
Hoofdauteurs: Abegglen, Lisa M., Caulin, Aleah F., Chan, Ashley, Lee, Kristy, Robinson, Rosann, Campbell, Michael S., Kiso, Wendy K., Schmitt, Dennis L., Waddell, Peter J, Bhaskara, Srividya, Jensen, Shane T., Maley, Carlo C., Schiffman, Joshua D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858328/
https://ncbi.nlm.nih.gov/pubmed/26447779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2015.13134
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