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A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive

African trypanosomes are mammalian pathogens that must regularly change their protein coat to survive in the host bloodstream. Chronic trypanosome infections are potentiated by their ability to access a deep genomic repertoire of Variant Surface Glycoprotein (VSG) genes and switch from the expressio...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Hovel-Miner, Galadriel, Mugnier, Monica R., Goldwater, Benjamin, Cross, George A. M., Papavasiliou, F. Nina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858185/
https://ncbi.nlm.nih.gov/pubmed/27149665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005994
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