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Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei
Trypanosoma brucei is a master of antigenic variation and immune response evasion. Utilizing a genomic repertoire of more than 1000 Variant Surface Glycoprotein-encoding genes (VSGs), T. brucei can change its protein coat by “switching” from the expression of one VSG to another. Each active VSG is m...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431348/ https://ncbi.nlm.nih.gov/pubmed/22952449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002900 |
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