A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive

African trypanosomes are mammalian pathogens that must regularly change their protein coat to survive in the host bloodstream. Chronic trypanosome infections are potentiated by their ability to access a deep genomic repertoire of Variant Surface Glycoprotein (VSG) genes and switch from the expressio...

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Udgivet i:PLoS Genet
Main Authors: Hovel-Miner, Galadriel, Mugnier, Monica R., Goldwater, Benjamin, Cross, George A. M., Papavasiliou, F. Nina
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858185/
https://ncbi.nlm.nih.gov/pubmed/27149665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005994
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