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A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive

African trypanosomes are mammalian pathogens that must regularly change their protein coat to survive in the host bloodstream. Chronic trypanosome infections are potentiated by their ability to access a deep genomic repertoire of Variant Surface Glycoprotein (VSG) genes and switch from the expressio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Hovel-Miner, Galadriel, Mugnier, Monica R., Goldwater, Benjamin, Cross, George A. M., Papavasiliou, F. Nina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858185/
https://ncbi.nlm.nih.gov/pubmed/27149665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005994
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