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An endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei
Trypanosoma brucei is the causative agent of African Sleeping Sickness in humans and one of the causes of Nagana in cattle. This protozoan parasite evades the host immune system by antigenic variation, a periodic switching of its variant surface glycoprotein (VSG) coat. VSG switching is spontaneous...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688456/ https://ncbi.nlm.nih.gov/pubmed/19369939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07982 |
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