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Mannose Receptor Is Required for Optimal Induction of Vaccine-Induced T-Helper Type 17 Cells and Resistance to Blastomyces dermatitidis Infection

We investigated how innate sensing by the mannose receptor (MR) influences the development of antifungal immunity. We demonstrate that MR senses mannan on the surface of attenuated Blastomyces dermatitidis vaccine yeast and that MR(−/−) mice demonstrate impaired vaccine immunity against lethal exper...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Wang, Huafeng, LeBert, Vanessa, Li, Mengyi, Lerksuthirat, Tassanee, Galles, Kevin, Klein, Bruce, Wüthrich, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857467/
https://ncbi.nlm.nih.gov/pubmed/26931447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw010
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