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Mannose Receptor Is Required for Optimal Induction of Vaccine-Induced T-Helper Type 17 Cells and Resistance to Blastomyces dermatitidis Infection

We investigated how innate sensing by the mannose receptor (MR) influences the development of antifungal immunity. We demonstrate that MR senses mannan on the surface of attenuated Blastomyces dermatitidis vaccine yeast and that MR(−/−) mice demonstrate impaired vaccine immunity against lethal exper...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Wang, Huafeng, LeBert, Vanessa, Li, Mengyi, Lerksuthirat, Tassanee, Galles, Kevin, Klein, Bruce, Wüthrich, Marcel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857467/
https://ncbi.nlm.nih.gov/pubmed/26931447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw010
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