Interleukin 1 Enhances Vaccine-Induced Antifungal T-Helper 17 Cells and Resistance Against Blastomyces dermatitidis Infection

Vaccine-induced T-helper 17 (Th17) cells are necessary and sufficient to protect against fungal infection. Although live fungal vaccines are efficient in driving protective Th17 responses and immunity, attenuated fungi may not be safe for human use. Heat-inactivated formulations and subunit vaccines...

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Autors principals: Wüthrich, Marcel, LeBert, Vanessa, Galles, Kevin, Hu-Li, Jane, Ben-Sasson, Shlomo Z., Paul, William E., Klein, Bruce S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762382/
https://ncbi.nlm.nih.gov/pubmed/23788728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit283
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