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The C-Type Lectin Receptor MCL Mediates Vaccine-Induced Immunity against Infection with Blastomyces dermatitidis

C-type lectin receptors (CLRs) are essential in shaping the immune response to fungal pathogens. Vaccine-induced resistance requires Dectin-2 to promote differentiation of antifungal Th1 and Th17 cells. Since Dectin-2 and MCL heterodimerize and both CLRs use FcRγ as the signaling adaptor, we investi...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Wang, Huafeng, Li, Mengyi, Lerksuthirat, Tassanee, Klein, Bruce, Wüthrich, Marcel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771354/
https://ncbi.nlm.nih.gov/pubmed/26667836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01263-15
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