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Wnt pathway activation by ADP-ribosylation

Wnt/β-catenin signalling directs fundamental processes during metazoan development and can be aberrantly activated in cancer. Wnt stimulation induces the recruitment of the scaffold protein Axin from an inhibitory destruction complex to a stimulatory signalosome. Here we analyse the early effects of...

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Pubblicato in:Nat Commun
Autori principali: Yang, Eungi, Tacchelly-Benites, Ofelia, Wang, Zhenghan, Randall, Michael P., Tian, Ai, Benchabane, Hassina, Freemantle, Sarah, Pikielny, Claudio, Tolwinski, Nicholas S., Lee, Ethan, Ahmed, Yashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857404/
https://ncbi.nlm.nih.gov/pubmed/27138857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11430
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