Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma

BACKGROUND: Scleroderma is an antigen-driven T cell-mediated autoimmune disease. Presence of anti-topoisomerase-I antibodies is associated with pulmonary fibrosis and predicts increased mortality. Characterization of autoreactive T lymphocytes may shed light on disease pathogenesis and serve as a bi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arthritis Res Ther
Egile Nagusiak: Fava, Andrea, Cimbro, Raffaello, Wigley, Fredrick M., Liu, Qing-Rong, Rosen, Antony, Boin, Francesco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857293/
https://ncbi.nlm.nih.gov/pubmed/27145754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0993-2
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