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T Cell Polarization Identifies Distinct Clinical Phenotypes in Scleroderma Lung Disease

OBJECTIVE: Lung involvement is the leading cause of morbidity and mortality in systemic sclerosis (SSc; scleroderma), and interstitial lung disease (ILD) is the most common pulmonary manifestation. An abnormal profibrotic Th2/Tc2-polarized T cell response is postulated to mediate tissue damage and f...

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Bibliografische gegevens
Hoofdauteurs: Boin, Francesco, De Fanis, Umberto, Bartlett, Susan J., Wigley, Fredrick M., Rosen, Antony, Casolaro, Vincenzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662772/
https://ncbi.nlm.nih.gov/pubmed/18383361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23406
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