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T Cell Polarization Identifies Distinct Clinical Phenotypes in Scleroderma Lung Disease
OBJECTIVE: Lung involvement is the leading cause of morbidity and mortality in systemic sclerosis (SSc; scleroderma), and interstitial lung disease (ILD) is the most common pulmonary manifestation. An abnormal profibrotic Th2/Tc2-polarized T cell response is postulated to mediate tissue damage and f...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662772/ https://ncbi.nlm.nih.gov/pubmed/18383361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23406 |
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