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Scleroderma Autoantigens Are Uniquely Fragmented by Metal-catalyzed Oxidation Reactions: Implications for Pathogenesis

The observation that revelation of immunocryptic epitopes in self antigens may initiate the autoimmune response has prompted the search for processes which induce novel fragmentation of autoantigens as potential initiators of autoimmunity. The reversible ischemia reperfusion which characterizes scle...

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Detalles Bibliográficos
Main Authors: Casciola-Rosen, Livia, Wigley, Fredrick, Rosen, Antony
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196102/
https://ncbi.nlm.nih.gov/pubmed/8996243
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