Autoantigens targeted in scleroderma patients with vascular disease are enriched in endothelial lineage cells

OBJECTIVE: Scleroderma patients with autoantibodies to centromere proteins (CENPs) and/or interferon-inducible protein 16 (IFI16) are at increased risk of severe vascular complications. We set out to define whether these autoantigens are enriched in cells of the vasculature. METHODS: Successive stag...

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Veröffentlicht in:Arthritis Rheumatol
Hauptverfasser: McMahan, Zsuzsanna H., Cottrell, Tricia R., Wigley, Fredrick M., Antiochos, Brendan, Zambidis, Elias T., Park, Tea Soon, Halushka, Marc K., Gutierrez-Alamillo, Laura, Cimbro, Raffaello, Rosen, Antony, Casciola-Rosen, Livia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042822/
https://ncbi.nlm.nih.gov/pubmed/27159521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39743
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