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Quantifying the ion atmosphere of unfolded, single-stranded nucleic acids using equilibrium dialysis and single-molecule methods

To form secondary structure, nucleic acids (NAs) must overcome electrostatic strand–strand repulsion, which is moderated by the surrounding atmosphere of screening ions. The free energy of NA folding therefore depends on the interactions of this ion atmosphere with both the folded and unfolded state...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Jacobson, David R., Saleh, Omar A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856996/
https://ncbi.nlm.nih.gov/pubmed/27036864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw196
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