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Quantifying the ion atmosphere of unfolded, single-stranded nucleic acids using equilibrium dialysis and single-molecule methods

To form secondary structure, nucleic acids (NAs) must overcome electrostatic strand–strand repulsion, which is moderated by the surrounding atmosphere of screening ions. The free energy of NA folding therefore depends on the interactions of this ion atmosphere with both the folded and unfolded state...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Jacobson, David R., Saleh, Omar A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856996/
https://ncbi.nlm.nih.gov/pubmed/27036864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw196
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