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Single-stranded nucleic acid elasticity arises from internal electrostatic tension

Understanding of the conformational ensemble of flexible polyelectrolytes, such as single-stranded nucleic acids (ssNAs), is complicated by the interplay of chain backbone entropy and salt-dependent electrostatic repulsions. Molecular elasticity measurements are sensitive probes of the statistical c...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jacobson, David R., McIntosh, Dustin B., Stevens, Mark J., Rubinstein, Michael, Saleh, Omar A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441769/
https://ncbi.nlm.nih.gov/pubmed/28461493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701132114
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