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Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer’s disease

Over the past two decades, many studies have identified significant contributions of toxic β-amyloid peptides (Aβ) to the etiology of Alzheimer’s disease (AD), which is the most common age-dependent neurodegenerative disease. AD is also recognized as a disease of synaptic failure. Aβ, generated by s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurosci Biobehav Rev
Egile Nagusiak: Yan, Riqiang, Fan, Qingyuan, Zhou, John, Vassar, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856578/
https://ncbi.nlm.nih.gov/pubmed/27044452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2016.03.025
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