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Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling
Inhibition of BACE1 is being pursued as a therapeutic target to treat patients suffering from Alzheimer’s disease because BACE1 is the sole β-secretase that generates β-amyloid peptide. Knowledge regarding other cellular functions of BACE1 is therefore critical for the safe use of BACE1 inhibitors i...
Kaydedildi:
| Yayımlandı: | J Neurochem |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833723/ https://ncbi.nlm.nih.gov/pubmed/26465092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13395 |
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