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Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer’s disease
Over the past two decades, many studies have identified significant contributions of toxic β-amyloid peptides (Aβ) to the etiology of Alzheimer’s disease (AD), which is the most common age-dependent neurodegenerative disease. AD is also recognized as a disease of synaptic failure. Aβ, generated by s...
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| Izdano u: | Neurosci Biobehav Rev |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856578/ https://ncbi.nlm.nih.gov/pubmed/27044452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2016.03.025 |
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